UPCOMING EVENTS: GENETIC TESTS AND GUT MICROBIOME – 9 SEPTEMBER 2024

UPCOMING EVENTS: GENETIC TESTS AND GUT MICROBIOME – 9 SEPTEMBER

Pharmacogenetics test

Optimize drug treatments based on your DNA

MyPharma analyzes your pharmacogenetic profile to identify which drugs work best according to your genetics, personalize dosing, and reduce the risk of adverse effects.

Overgenes MyPharma pharmacogenetics test for personalized treatment
Non-invasive Saliva sample, painless and suitable for any age
Once in a lifetime Your pharmacogenetic profile doesn’t change: the analysis is performed only once
4 panels General · Chronic Pain · Neuropsychiatry · Oncology
Personalized medicine

Pharmacogenetics optimizes treatment safety and effectiveness

Pharmacogenetics studies genetic variability in relation to drug response. Knowing this information makes it possible to determine the most suitable drug for each patient and personalize the dosage.

This becomes especially relevant in situations where, due to the severity of the disease, it is crucial to ensure treatment effectiveness and minimize the risk of toxicity.

What pharmacogenetics makes possible

  • Identify the drug most likely to be effective based on the genetic profile
  • Adjust the optimal dose, avoiding under- or overdosing
  • Reduce the risk of adverse reactions and toxicity
  • Avoid drug interactions associated with genetic metabolism
  • Genetic information valid for life, for any future treatment
Available panels

Four specialized tests for every clinical need

Overgenes offers different MyPharma panels, each analyzing specific groups of drugs adapted to different therapeutic areas.

General

MyPharma General

110+
drugs analyzed

The most complete panel. Covers the most common and widely used drugs across 24 therapeutic categories.

Pain

MyPharma Pain

75
drugs analyzed

Specialized in chronic pain. NSAIDs, opioids, anesthetics, anxiolytics and pain management adjuvants.

Neuro

MyPharma Neuro

70+
drugs analyzed

Drugs for mental health. Antidepressants, antipsychotics, antiepileptics, anxiolytics, ADHD and dementia.

Onco

MyPharma Onco

25
drugs analyzed

Oncology treatment. Chemotherapy, targeted therapies, immunotherapy and management of adverse effects.

Panel comparison

Which drug categories does each test analyze?

Each MyPharma panel covers specific groups of medications. Check the table to identify the most suitable panel based on the patient’s treatment.

Full category
Partially included
Not included
Therapeutic category General Pain Neuro Onco
Pain and anesthesia
NSAIDs
Opioids
Anesthetics
Antipyretics
Neurology and psychiatry
Antidepressants
Antipsychotics
Antiepileptics
Anxiolytics
ADHD
Dementia
Smoking cessation
Cardiovascular and metabolism
Anticoagulants
Antiplatelet agents
Antihypertensives
Beta-blockers
Antiarrhythmics
Statins
Antidiabetics
Diuretics
Digestive, immunology and other
Proton pump inhibitors
Immunosuppressants
Anti-infectives
Corticosteroids
Antiemetics
Respiratory
Antimigraine
Oncology
Chemotherapy and targeted therapies
Total drugs analyzed 110+ 75 70+ 25
Process

How the pharmacogenetics test works

A simple, non-invasive process designed to fit into clinical practice.

Receive the test

The user receives instructions to correctly collect the sample.

Collect the sample

DNA is obtained through a saliva sample, painlessly and non-invasively.

Genetic analysis

The sample is processed to analyze genetic variants involved in drug response.

Results

The report details drug compatibility, clinical annotations and therapeutic recommendations.

MyPharma Report

Detailed clinical information for the medical specialist

The report provides the specialist with a high-value, easy-to-interpret clinical tool for optimizing therapeutic decisions on a personalized basis.

  • Drug compatibility classified by impact level: none, limited, moderate or high
  • Genetic variants identified (SNPs and haplotypes) with associated gene and level of evidence (PharmGKB, CPIC, DPWG)
  • Specific clinical annotations: efficacy, dosage, toxicity and pharmacokinetics
  • Therapeutic recommendation based on CPIC, DPWG, FDA and EMA guidelines
  • Complete metabolic profile with haplotypes and metabolizer type (CYP2D6, CYP2C19, CYP3A5, etc.)
Content of the Overgenes MyPharma report Content of the Overgenes MyPharma report
Scientific evidence

An approach based on the strongest available pharmacogenetic evidence

The MyPharma tests integrate data from the leading international pharmacogenetics databases and consortia to offer recommendations with the highest level of evidence.

PharmGKB

The largest publicly accessible pharmacogenomics database, funded by the NIH and founded at Stanford.

CPIC & DPWG

Clinical guidelines from the leading international pharmacogenetics consortia for decision-making.

FDA & EMA

Regulatory annotations from the American and European medicines agencies incorporated into the analysis.

Illumina GSA

Microarray technology that analyzes ~700,000 genetic variants with reliable, reproducible results.

Frequently asked questions

Frequently asked questions about pharmacogenetics

What is pharmacogenetics and what is it for?

Pharmacogenetics studies how each person’s genetic variants influence their response to medications. It allows the doctor to select the most suitable drug, personalize the dosage, and anticipate the risk of adverse effects before starting treatment.

What’s the difference between the 4 MyPharma panels?

Each panel specializes in a specific therapeutic area:

  • General: the most complete, with more than 110 drugs across 24 categories (cardiovascular, diabetes, pain, psychiatry, oncology, etc.)
  • Pain: 75 drugs focused on chronic pain (NSAIDs, opioids, anesthetics, anxiolytics, corticosteroids)
  • Neuro: more than 70 mental health drugs (antidepressants, antipsychotics, antiepileptics, ADHD, dementia)
  • Onco: 25 oncology drugs (chemotherapy, targeted therapies, immunotherapy)
Does the test need to be repeated over time?

No. Your genetic profile doesn’t change throughout life. The test result remains valid permanently and can be consulted every time a new treatment is prescribed.

How is the sample collected?

The sample is obtained non-invasively through saliva. It doesn’t require blood collection, is painless and suitable for any age.

Is supervision by a medical professional required?

The results of the pharmacogenetic test should be interpreted by a medical professional. The report provides a tool to support therapeutic decision-making, but the final decision always rests with the prescribing physician based on a complete evaluation of the patient.

What does the results report contain?

The report includes the drug compatibility of each medication analyzed (classified by impact level), the genetic variants identified along with their level of evidence, specific clinical annotations, and therapeutic recommendations based on the CPIC, DPWG, FDA and EMA guidelines.

How long do results take?

Results are available within an approximate maximum of 20 business days after the sample is received at the lab.

Take the step

Interested in the pharmacogenetics test?

Contact our team for more information about the MyPharma tests or to request a personalized pharmacogenetic study.

NOVEDAD

Ya puedes comprar tus análisis online

La tienda online de Overgenes ya está disponible. Accede a nuestros test de genética, microbiota y epigenética desde una única plataforma.

Descubrir la tienda
¡Promoción especial!
2 tests -25%
3 tests -30%
4 tests -35%
5+ tests -40%

* Descuento aplicable únicamente cuando todos los test genéticos del pedido corresponden a una misma persona.

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